Human NONO activation kit by CRISPRa

SKU GA103231

NONO CRISPRa kit - CRISPR gene activation of human non-POU domain containing octamer binding

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NONO
• Locus ID: 4841
• Components:

  GA103231G1, NONO gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103231G2, NONO gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103231G3, NONO gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001145408, NM_001145409, NM_001145410, NM_007363
• UniProt ID: Q15233
• Synonyms: MRXS34; NMT55; NRB54; P54; P54NRB; PPP1R114
• Summary: This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009]