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Human NEK3 activation kit by CRISPRa

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SKU
GA103170
NEK3 CRISPRa kit - CRISPR gene activation of human NIMA related kinase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC205775 NEK3 (Myc-DDK-tagged)-Human NIMA (never in mitosis gene a)-related kinase 3 (NEK3), transcript variant 2
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Other products for "NEK3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NEK3
Locus ID 4752
Components

GA103170G1, NEK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103170G2, NEK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103170G3, NEK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001146099, NM_002498, NM_152720, NR_027415
UniProt ID P51956
Synonyms HSPK36
Summary This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Two functional alleles for this gene have been identified in humans. The reference genome assembly (GRCh38) represents a functional allele that is associated with the inclusion of an additional coding exon in protein-coding transcripts, compared to an alternate functional allele that lacks the exon. provided by RefSeq, Sep 2019
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Other Versions
SKU Description Size Price
KN405775 NEK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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