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Human NEDD4 activation kit by CRISPRa

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SKU
GA103159
NEDD4 CRISPRa kit - CRISPR gene activation of human NEDD4 E3 ubiquitin protein ligase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC221706 NEDD4 (Myc-DDK-tagged)-Human neural precursor cell expressed, developmentally down-regulated 4 (NEDD4), transcript variant 1
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Other products for "NEDD4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NEDD4
Locus ID 4734
Components

GA103159G1, NEDD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103159G2, NEDD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103159G3, NEDD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001284338, NM_001284339, NM_001284340, NM_006154, NM_198400, NR_104302, NM_001329212
UniProt ID P46934
Synonyms NEDD4-1; RPF1
Summary This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. provided by RefSeq, Jul 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN412738 NEDD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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