Human MYO7B activation kit by CRISPRa

SKU GA103087

MYO7B CRISPRa kit - CRISPR gene activation of human myosin VIIB

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYO7B
• Locus ID: 4648
• Components:

  GA103087G1, MYO7B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103087G2, MYO7B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103087G3, MYO7B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001080527, NM_183371
• UniProt ID: Q6PIF6
• Synonyms: DKFZp686A08248
• Summary: The protein encoded by this gene is found in brush border microvilli of epithelial cells in the intestines and kidneys. The encoded protein is involved in linking protocadherins to the actin cytoskeleton and is essential for proper microvilli function. This protein aids in the accumulation of intermicrovillar adhesion components such as harmonin and ANKS4B, and this accumulation is necessary for normal brush border action. [provided by RefSeq, Jan 2017]