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Human MTHFR activation kit by CRISPRa

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SKU
GA103015
MTHFR CRISPRa kit - CRISPR gene activation of human methylenetetrahydrofolate reductase
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC208588 MTHFR (Myc-DDK-tagged)-Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR)
10 ug
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Other products for "MTHFR"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MTHFR
Locus ID 4524
Components

GA103015G1, MTHFR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103015G2, MTHFR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103015G3, MTHFR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001330358, NM_005957
UniProt ID P42898
Summary The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN408588 MTHFR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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