Human MSH4 activation kit by CRISPRa

SKU
GA102979
MSH4 CRISPRa kit - CRISPR gene activation of human mutS homolog 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MSH4
Locus ID 4438
Components

GA102979G1, MSH4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102979G2, MSH4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102979G3, MSH4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002440
UniProt ID O15457
Synonyms mutS homolog 4; mutS homolog 4 (E. coli); OTTHUMP00000011349
Summary This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. provided by RefSeq, Aug 2011
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Other Versions
SKU Description Size Price
KN406059 MSH4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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