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Human MRE11 activation kit by CRISPRa

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SKU
GA102971
MRE11 CRISPRa kit - CRISPR gene activation of human MRE11 homolog, double strand break repair nuclease
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350181 Rabbit Polyclonal Anti-MRE11A Antibody
100 ul
$205.00
RC209414 MRE11A (Myc-DDK-tagged)-Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1
10 ug
$648.00

Other products for "MRE11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MRE11
Locus ID 4361
Components

GA102971G1, MRE11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102971G2, MRE11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102971G3, MRE11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_005590, NM_005591, NM_001330347
UniProt ID P49959
Synonyms ATLD; HNGS1; MRE11; MRE11B
Summary This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN209414 MRE11A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209414BN MRE11A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209414LP MRE11A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209414RB MRE11A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409414 MRE11A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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