Human MMP8 activation kit by CRISPRa

SKU
GA102937
MMP8 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 8
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMP8
Locus ID 4317
Components

GA102937G1, MMP8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102937G2, MMP8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102937G3, MMP8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001304441, NM_001304442, NM_002424
UniProt ID P22894
Synonyms CLG1; HNC; MMP-8; PMNL-CL
Summary This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2015
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Other Versions
SKU Description Size Price
KN410391 MMP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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