Human MIPEP activation kit by CRISPRa

SKU GA102912

MIPEP CRISPRa kit - CRISPR gene activation of human mitochondrial intermediate peptidase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MIPEP
• Locus ID: 4285
• Components:

  GA102912G1, MIPEP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102912G2, MIPEP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102912G3, MIPEP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005932
• UniProt ID: Q99797
• Synonyms: HMIP; MIP
• Summary: The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq, Jul 2008]