Human SMCP activation kit by CRISPRa

SKU GA102851

SMCP CRISPRa kit - CRISPR gene activation of human sperm mitochondria associated cysteine rich protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SMCP
• Locus ID: 4184
• Components:

  GA102851G1, SMCP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102851G2, SMCP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102851G3, SMCP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_030663
• UniProt ID: P49901
• Synonyms: HSMCSGEN1; MCS; MCSP
• Summary: Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008]