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Human MCM6 activation kit by CRISPRa

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SKU
GA102848
MCM6 CRISPRa kit - CRISPR gene activation of human minichromosome maintenance complex component 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
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RC207097 MCM6 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 6 (MCM6)
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Other products for "MCM6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MCM6
Locus ID 4175
Components

GA102848G1, MCM6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102848G2, MCM6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102848G3, MCM6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005915
UniProt ID Q14566
Synonyms MCG40308; Mis5; P105MCM
Summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. provided by RefSeq, May 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN407097 MCM6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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