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Human MCM3 activation kit by CRISPRa

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SKU
GA102845
MCM3 CRISPRa kit - CRISPR gene activation of human minichromosome maintenance complex component 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC200208 MCM3 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 3 (MCM3)
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Other products for "MCM3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MCM3
Locus ID 4172
Components

GA102845G1, MCM3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102845G2, MCM3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102845G3, MCM3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001270472, NM_002388, NR_158966, NM_001366369, NM_001366371, NM_001366375, NR_158964, NM_001366370, NM_001366372, NM_001366373, NM_001366374, NR_158963, NR_158965
UniProt ID P25205
Synonyms HCC5; P1-MCM3; P1.h; RLFB
Summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2018
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Other Versions
SKU Description Size Price
KN400208 MCM3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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