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Human Myelin Basic Protein (MBP) activation kit by CRISPRa

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SKU
GA102833
MBP CRISPRa kit - CRISPR gene activation of human myelin basic protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA336919 Mouse Monoclonal MBP Antibody (2H9)
100 ul
$635.00
RC215746 MBP (Myc-DDK-tagged)-Human myelin basic protein (MBP), transcript variant 1
10 ug
$450.00

Other products for "MBP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MBP
Locus ID 4155
Components

GA102833G1, Myelin Basic Protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102833G2, Myelin Basic Protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102833G3, Myelin Basic Protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001025081, NM_001025090, NM_001025092, NM_001025094, NM_001025098, NM_001025100, NM_001025101, NM_002385, N20370
UniProt ID P02686
Synonyms MGC99675
Summary The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN400710 MBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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