Human MANBA activation kit by CRISPRa

SKU GA102808

MANBA CRISPRa kit - CRISPR gene activation of human mannosidase beta

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MANBA
• Locus ID: 4126
• Components:

  GA102808G1, MANBA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102808G2, MANBA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102808G3, MANBA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005908
• UniProt ID: O00462
• Synonyms: MANB1
• Summary: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]