Human MAD2 (MAD2L1) activation kit by CRISPRa

SKU GA102773

MAD2L1 CRISPRa kit - CRISPR gene activation of human mitotic arrest deficient 2 like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MAD2L1
• Locus ID: 4085
• Components:

  GA102773G1, MAD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102773G2, MAD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102773G3, MAD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002358
• UniProt ID: Q13257
• Synonyms: HSMAD2; MAD2
• Summary: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]