Human LTBP2 activation kit by CRISPRa

SKU GA102747

LTBP2 CRISPRa kit - CRISPR gene activation of human latent transforming growth factor beta binding protein 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LTBP2
• Locus ID: 4053
• Components:

  GA102747G1, LTBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102747G2, LTBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102747G3, LTBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000428
• UniProt ID: Q14767
• Synonyms: C14orf141; GLC3D; LTBP3; MSPKA; MSTP031; WMS3
• Summary: The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. [provided by RefSeq, Jul 2008]