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Human LRP1 activation kit by CRISPRa

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SKU
GA102732
LRP1 CRISPRa kit - CRISPR gene activation of human LDL receptor related protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$310.00
RC218369 LRP1 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 1 (LRP1)
10 ug
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Other products for "LRP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LRP1
Locus ID 4035
Components

GA102732G1, LRP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102732G2, LRP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102732G3, LRP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002332
UniProt ID Q07954
Synonyms A2MR; APOER; APR; CD91; IGFBP3R; LRP; LRP1A; TGFBR5
Summary This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN418369 LRP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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