Human LIMS1 activation kit by CRISPRa

SKU
GA102701
LIMS1 CRISPRa kit - CRISPR gene activation of human LIM zinc finger domain containing 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LIMS1
Locus ID 3987
Components

GA102701G1, LIMS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102701G2, LIMS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102701G3, LIMS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001193482, NM_001193483, NM_001193484, NM_001193485, NM_001193488, NM_004987
UniProt ID P48059
Synonyms PINCH; PINCH-1; PINCH1
Summary The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2010
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Other Versions
SKU Description Size Price
KN402765 LIMS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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