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Human Leptin Receptor (LEPR) activation kit by CRISPRa

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SKU
GA102678
LEPR CRISPRa kit - CRISPR gene activation of human leptin receptor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA302673 Goat Polyclonal Antibody against Leptin Receptor
100 ug
$565.00
RC223816 LEPR (Myc-DDK-tagged)-Human leptin receptor (LEPR), transcript variant 1
10 ug
$1,014.00

Other products for "LEPR"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LEPR
Locus ID 3953
Components

GA102678G1, Leptin Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102678G2, Leptin Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102678G3, Leptin Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001003679, NM_001003680, NM_001198687, NM_001198688, NM_001198689, NM_002303
UniProt ID P48357
Synonyms CD295; LEP-R; LEPRD; OB-R; OBR
Summary The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).provided by RefSeq, Nov 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN218456 LEPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218456BN LEPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218456LP LEPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218456RB LEPR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN418456 LEPR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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