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Human Karyopherin beta 3 (IPO5) activation kit by CRISPRa

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SKU
GA102607
IPO5 CRISPRa kit - CRISPR gene activation of human importin 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA811926 IPO5 mouse monoclonal antibody,clone OTI3B8
100 ul
$447.00
RC207221 IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5)
10 ug
$589.00 $971.00

Other products for "IPO5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IPO5
Locus ID 3843
Components

GA102607G1, Karyopherin beta 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102607G2, Karyopherin beta 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102607G3, Karyopherin beta 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002271
UniProt ID O00410
Synonyms IMB3; imp5; KPNB3; Pse1; RANBP5
Summary Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN407221 IPO5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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