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Human KCNN3 activation kit by CRISPRa

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SKU
GA102556
KCNN3 CRISPRa kit - CRISPR gene activation of human potassium calcium-activated channel subfamily N member 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA368611 KCNN3 rabbit polyclonal antibody
100 ul
$310.00
RC211543 KCNN3 (Myc-DDK-tagged)-Human potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (KCNN3), transcript variant 1
10 ug
$673.00

Other products for "KCNN3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KCNN3
Locus ID 3782
Components

GA102556G1, KCNN3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102556G2, KCNN3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102556G3, KCNN3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001204087, NM_002249, NM_170782, NM_001365838, NM_001365837
UniProt ID Q9UGI6
Synonyms hSK3; KCa2.3; SK3; SKCA3
Summary Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN408350 KCNN3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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