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Human KCNA5 activation kit by CRISPRa

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SKU
GA102517
KCNA5 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily A member 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA314120 Rabbit polyclonal anti-KCNA5 antibody
100 ul
$380.00
RC219793 KCNA5 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5)
10 ug
$856.00

Other products for "KCNA5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KCNA5
Locus ID 3741
Components

GA102517G1, KCNA5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102517G2, KCNA5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102517G3, KCNA5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002234
UniProt ID P22460
Synonyms ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1
Summary Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). provided by RefSeq, May 2012
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Resources
Other Versions
SKU Description Size Price
KN419793 KCNA5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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