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Human Integrin beta 7 (ITGB7) activation kit by CRISPRa

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SKU
GA102484
ITGB7 CRISPRa kit - CRISPR gene activation of human integrin subunit beta 7
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA351299 Rabbit Polyclonal Anti-ITGB7 Antibody
100 ul
$205.00
RC204193 ITGB7 (Myc-DDK-tagged)-Human integrin, beta 7 (ITGB7)
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Other products for "ITGB7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGB7
Locus ID 3695
Components

GA102484G1, Integrin beta 7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102484G2, Integrin beta 7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102484G3, Integrin beta 7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000889, NR_104181
UniProt ID P26010
Synonyms integrin, beta 7; integrin beta 7 subunit
Summary This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. provided by RefSeq, Sep 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN404193 ITGB7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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