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Human CD11c (ITGAX) activation kit by CRISPRa

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SKU
GA102476
ITGAX CRISPRa kit - CRISPR gene activation of human integrin subunit alpha X
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC223262 ITGAX (Myc-DDK-tagged)-Human integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX)
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Other products for "ITGAX"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGAX
Locus ID 3687
Components

GA102476G1, CD11c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102476G2, CD11c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102476G3, CD11c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000887, NM_001286375
UniProt ID P20702
Synonyms CD11C; SLEB6
Summary This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2013
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Documents
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Other Versions
SKU Description Size Price
KN423262 ITGAX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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