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Human IRF3 activation kit by CRISPRa

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SKU
GA102454
IRF3 CRISPRa kit - CRISPR gene activation of human interferon regulatory factor 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500465 Anti-IRF3 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2) 100 ul
$447.00
RC209951 IRF3 (Myc-DDK-tagged)-Human interferon regulatory factor 3 (IRF3), transcript variant 1
10 ug
$457.00

Other products for "IRF3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IRF3
Locus ID 3661
Components

GA102454G1, IRF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102454G2, IRF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102454G3, IRF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001197122, NM_001197123, NM_001197124, NM_001197125, NM_001197126, NM_001197127, NM_001197128, NM_001571, NR_045568
UniProt ID Q14653
Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. provided by RefSeq, Sep 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN209951 IRF3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209951BN IRF3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209951LP IRF3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209951RB IRF3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409951 IRF3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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