Human IRAK2 activation kit by CRISPRa

SKU GA102450

IRAK2 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor associated kinase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: IRAK2
• Locus ID: 3656
• Components:

  GA102450G1, IRAK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102450G2, IRAK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102450G3, IRAK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001570
• UniProt ID: O43187
• Synonyms: IRAK-2
• Summary: IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008]