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Human Integrin alpha 6 (ITGA6) activation kit by CRISPRa

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SKU
GA102449
ITGA6 CRISPRa kit - CRISPR gene activation of human integrin subunit alpha 6
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC221990 ITGA6 (Myc-DDK-tagged)-Human integrin, alpha 6 (ITGA6), transcript variant 2
10 ug
$934.00

Other products for "ITGA6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGA6
Locus ID 3655
Components

GA102449G1, Integrin alpha 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102449G2, Integrin alpha 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102449G3, Integrin alpha 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000210, NM_001079818, NM_001316306, NM_001365529, NM_001365530
UniProt ID P23229
Synonyms CD49f; ITGA6B; VLA-6
Summary The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN421990 ITGA6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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