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Human IL10RA activation kit by CRISPRa

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SKU
GA102397
IL10RA CRISPRa kit - CRISPR gene activation of human interleukin 10 receptor subunit alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "IL10RA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL10RA
Locus ID 3587
Components

GA102397G1, IL10RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102397G2, IL10RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102397G3, IL10RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001558, NR_026691
UniProt ID Q13651
Synonyms CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R
Summary The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. provided by RefSeq, Jan 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN407020 IL10RA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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