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Human IL5RA activation kit by CRISPRa

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SKU
GA102385
IL5RA CRISPRa kit - CRISPR gene activation of human interleukin 5 receptor subunit alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "IL5RA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL5RA
Locus ID 3568
Components

GA102385G1, IL5RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102385G2, IL5RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102385G3, IL5RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000564, NM_001243099, NM_175724, NM_175725, NM_175726, NM_175727, NM_175728
UniProt ID Q01344
Synonyms CD125; CDw125; HSIL5R3; IL5R
Summary The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. provided by RefSeq, Jul 2011
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Documents
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Other Versions
SKU Description Size Price
KN405386 IL5RA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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