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Human IL3RA activation kit by CRISPRa

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SKU
GA102381
IL3RA CRISPRa kit - CRISPR gene activation of human interleukin 3 receptor subunit alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "IL3RA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL3RA
Locus ID 3563
Components

GA102381G1, IL3RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102381G2, IL3RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102381G3, IL3RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001267713, NM_002183
UniProt ID P26951
Synonyms CD123; hIL-3Ra; IL3R; IL3RAY; IL3RX; IL3RY
Summary The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. provided by RefSeq, Jun 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN406420 IL3RA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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