Human IGFBP1 activation kit by CRISPRa

SKU
GA102353
IGFBP1 CRISPRa kit - CRISPR gene activation of human insulin like growth factor binding protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IGFBP1
Locus ID 3484
Components

GA102353G1, IGFBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102353G2, IGFBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102353G3, IGFBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000596, NM_001013029
UniProt ID P08833
Synonyms AFBP; hIGFBP-1; IBP1; IGF-BP25; PP12
Summary This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN409268 IGFBP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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