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Human IFIT2 activation kit by CRISPRa

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SKU
GA102323
IFIT2 CRISPRa kit - CRISPR gene activation of human interferon induced protein with tetratricopeptide repeats 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA346292 Rabbit Polyclonal Anti-IFIT2 Antibody
100 ul
$585.00
RC205582 IFIT2 (Myc-DDK-tagged)-Human interferon-induced protein with tetratricopeptide repeats 2 (IFIT2)
10 ug
$457.00

Other products for "IFIT2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IFIT2
Locus ID 3433
Components

GA102323G1, IFIT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102323G2, IFIT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102323G3, IFIT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001547
UniProt ID P09913
Synonyms cig42; G10P2; GARG-39; IFI-54; IFI-54K; IFI54; IFIT-2; ISG-54 K; ISG-54K; ISG54; P54
Summary IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN405582 IFIT2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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