Human HOXB9 activation kit by CRISPRa

SKU GA102203

HOXB9 CRISPRa kit - CRISPR gene activation of human homeobox B9

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HOXB9
• Locus ID: 3219
• Components:

  GA102203G1, HOXB9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102203G2, HOXB9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102203G3, HOXB9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024017
• UniProt ID: P17482
• Synonyms: HOX-2.5; HOX2; HOX2E
• Summary: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]