Human FOXA2 activation kit by CRISPRa

SKU GA102162

FOXA2 CRISPRa kit - CRISPR gene activation of human forkhead box A2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FOXA2
• Locus ID: 3170
• Components:

  GA102162G1, FOXA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102162G2, FOXA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102162G3, FOXA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021784, NM_153675
• UniProt ID: Q9Y261
• Synonyms: HNF3B; TCF3B
• Summary: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]