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Human ZBTB48 activation kit by CRISPRa

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SKU
GA102116
ZBTB48 CRISPRa kit - CRISPR gene activation of human zinc finger and BTB domain containing 48
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA329704 Rabbit Polyclonal Anti-ZBTB48 Antibody
100 ul
$585.00
RC202057 ZBTB48 (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 48 (ZBTB48)
10 ug
$630.00

Other products for "ZBTB48"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZBTB48
Locus ID 3104
Components

GA102116G1, ZBTB48 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102116G2, ZBTB48 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102116G3, ZBTB48 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001278647, NM_001278648, NM_005341
UniProt ID P10074
Synonyms HKR3; pp9964; ZNF855
Summary Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN402057 ZBTB48 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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