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Human TFIIA2 (GTF2A2) activation kit by CRISPRa

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SKU
GA102003
GTF2A2 CRISPRa kit - CRISPR gene activation of human general transcription factor IIA subunit 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA370444 GTF2A2 rabbit polyclonal antibody
100 ul
$310.00
RC201117 GTF2A2 (Myc-DDK-tagged)-Human general transcription factor IIA, 2, 12kDa (GTF2A2)
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$150.00

Other products for "GTF2A2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GTF2A2
Locus ID 2958
Components

GA102003G1, TFIIA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102003G2, TFIIA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102003G3, TFIIA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001320929, NM_001320930, NM_004492
UniProt ID P52657
Synonyms HsT18745; T18745; TF2A2; TFIIA; TFIIA-12; TFIIA-gamma; TFIIAS
Summary Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 PubMed 7724559).supplied by OMIM, Mar 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401117 GTF2A2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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