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Human NMDAR2B (GRIN2B) activation kit by CRISPRa

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SKU
GA101960
GRIN2B CRISPRa kit - CRISPR gene activation of human glutamate ionotropic receptor NMDA type subunit 2B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA309191 Rabbit Anti-NMDA NR2B Subunit Antibody
10 ug
$610.00
RC223623 GRIN2B (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B)
10 ug
$589.00 $1,904.00

Other products for "GRIN2B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRIN2B
Locus ID 2904
Components

GA101960G1, NMDAR2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101960G2, NMDAR2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101960G3, NMDAR2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000834
UniProt ID Q13224
Synonyms EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B
Summary This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN423623 GRIN2B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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