NMDAR2B (GRIN2B) Rabbit Polyclonal Antibody

SKU
TA309191
Rabbit Anti-NMDA NR2B Subunit Antibody
  $610.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1:1000, IHC: 1:1000-2000, IP: 3ug/200ug lysate
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein from the C-terminal region of the NR2B subunit
Buffer Lyophilized
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 180 kDa
Gene Name glutamate ionotropic receptor NMDA type subunit 2B
Database Link
Synonyms EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Systemic lupus erythematosus
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Documents
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file-alt Citations

Increased expression of fibronectin leucine-rich transmembrane protein 3 in the dorsal root ganglion induces neuropathic pain in rats
Yamada, Fujita, Hayano et al
J. Neurosci. (2019) 39 (38), 7615-7627 DOI: 10.1523/JNEUROSCI.0295-19.2019
AI Summary: OriGene products, specifically the anti-NR2B (GluN2B) antibody (TA309191) and the anti-phosphorylated (Tyr1472) NR2B (GluN2B) antibody (TA309196), were used in this study to detect changes in NR2B protein expression and phosphorylation, helping to elucidate the molecular mechanisms by which FLRT3 contributes to neuropathic pain in rats.
Snippet: antibodies against FLRT3 (1:500;AF2795, R&D Systems), NR2B (GluN2B) (1:500;224 TA309191, OriGene), phosphorylated (Tyr1472) NR2B (GluN2B;1:500;TA309196, 225 OriGene), β-actin (1:1000;4970L, Cell Singling Technology), or α-tubulin (1:1,000;226;- antibodies against FLRT3 (1:500
WB
Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B
Hayano, Takasu, Koyama et al
J. Exp. Med. (2016)
AI Summary: OriGene products anti-NR2B antibody (TA309191) and anti-phosphorylated (Tyr1472) NR2B antibody (TA309196) were used for immunodetection to investigate molecular changes in spinal cord tissue relevant to chronic pain mechanisms in this study.
Snippet: They were then incubated overnight at 4°C with anti-NR2B (1:500;TA309191;OriGene), anti-phosphorylated (Tyr1472) NR2B (1:500;TA309196;OriGene), or an anti–α-tubulin antibody (1:1,000;sc-5286;Santa Cruz Biotechnology, Inc.) in TBST buffer containing 1% BSA. After washing in TBST,
WB
Showing 1-2 of 2 papers.
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