Human GRIK5 activation kit by CRISPRa

SKU GA101957

GRIK5 CRISPRa kit - CRISPR gene activation of human glutamate ionotropic receptor kainate type subunit 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GRIK5
• Locus ID: 2901
• Components:

  GA101957G1, GRIK5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101957G2, GRIK5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101957G3, GRIK5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001301030, NM_002088
• UniProt ID: Q16478
• Synonyms: EAA2; GluK5; GRIK2; KA2
• Summary: This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]