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Human GRB10 activation kit by CRISPRa

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SKU
GA101943
GRB10 CRISPRa kit - CRISPR gene activation of human growth factor receptor bound protein 10
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA812343 GRB10 mouse monoclonal antibody,clone OTI5A6 100 ul
$447.00
RC206853 GRB10 (Myc-DDK-tagged)-Human growth factor receptor-bound protein 10 (GRB10), transcript variant 4
10 ug
$499.00

Other products for "GRB10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRB10
Locus ID 2887
Components

GA101943G1, GRB10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101943G2, GRB10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101943G3, GRB10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001001549, NM_001001550, NM_001001555, NM_005311, NM_001350814, NM_001350815, NM_001350816
UniProt ID Q13322
Synonyms Grb-10; GRB-IR; IRBP; MEG1; RSS
Summary The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Oct 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN406853 GRB10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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