Human MCHR (MCHR1) activation kit by CRISPRa

SKU GA101910

MCHR1 CRISPRa kit - CRISPR gene activation of human melanin concentrating hormone receptor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MCHR1
• Locus ID: 2847
• Components:

  GA101910G1, MCHR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101910G2, MCHR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101910G3, MCHR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005297
• UniProt ID: Q99705
• Synonyms: GPR24; MCH-1R; MCH1R; SLC-1; SLC1
• Summary: The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008]