MCHR (MCHR1) Rabbit Polyclonal Antibody

SKU TA351389

Rabbit Polyclonal Anti-MCHR1 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Human fetal liver and testis tissue, 293T and A172 cells, mouse brain and human fetal brain tissue; IHC: 50-200; Positive control: Human ovarian cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MCHR1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 46 kDa
• Gene Name: melanin concentrating hormone receptor 1
• Database Link:
  NP_005288
  Q99705
• Background: MCHR1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR1 does not seem to bind somatostatin.
• Synonyms: GPR24; MCH-1R; MCH1R; SLC-1; SLC1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction