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Human CD42b (GP1BA) activation kit by CRISPRa

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SKU
GA101878
GP1BA CRISPRa kit - CRISPR gene activation of human glycoprotein Ib platelet subunit alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC206598 GP1BA (Myc-DDK-tagged)-Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA)
10 ug
$583.00

Other products for "GP1BA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GP1BA
Locus ID 2811
Components

GA101878G1, CD42b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101878G2, CD42b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101878G3, CD42b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000173
UniProt ID P07359
Synonyms BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; GPIbA; GPIbalpha; VWDP
Summary Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. provided by RefSeq, Oct 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN406598 GP1BA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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