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Human GNRHR activation kit by CRISPRa

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SKU
GA101868
GNRHR CRISPRa kit - CRISPR gene activation of human gonadotropin releasing hormone receptor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA321121 Anti-GNRHR Rabbit Polyclonal Antibody
100 ul
$305.00
RC214403 GNRHR (Myc-DDK-tagged)-Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1
10 ug
$300.00

Other products for "GNRHR"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GNRHR
Locus ID 2798
Components

GA101868G1, GNRHR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101868G2, GNRHR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101868G3, GNRHR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000406, NM_001012763
UniProt ID P30968
Synonyms GNRHR1; GRHR; HH7; LHRHR; LRHR
Summary This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN414403 GNRHR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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