Human GNG7 activation kit by CRISPRa

SKU GA101860

GNG7 CRISPRa kit - CRISPR gene activation of human G protein subunit gamma 7

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNG7
• Locus ID: 2788
• Components:

  GA101860G1, GNG7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101860G2, GNG7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101860G3, GNG7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005145, NM_052847
• UniProt ID: O60262
• Synonyms: FLJ00058; guanine nucleotide binding protein (G protein), gamma 7
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).[UniProtKB/Swiss-Prot Function]