Human GNAL activation kit by CRISPRa

SKU GA101847

GNAL CRISPRa kit - CRISPR gene activation of human G protein subunit alpha L

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNAL
• Locus ID: 2774
• Components:

  GA101847G1, GNAL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101847G2, GNAL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101847G3, GNAL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001142339, NM_001261443, NM_001261444, NM_002071, NM_182978, NM_001369387
• UniProt ID: P38405
• Synonyms: DYT25
• Summary: This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]