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Human GCLC activation kit by CRISPRa

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SKU
GA101817
GCLC CRISPRa kit - CRISPR gene activation of human glutamate-cysteine ligase catalytic subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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$447.00
RC207915 GCLC (Myc-DDK-tagged)-Human glutamate-cysteine ligase, catalytic subunit (GCLC), transcript variant 1
10 ug
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Other products for "GCLC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GCLC
Locus ID 2729
Components

GA101817G1, GCLC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101817G2, GCLC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101817G3, GCLC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001197115, NM_001498
UniProt ID P48506
Synonyms GCL; GCS; GLCL; GLCLC
Summary Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.provided by RefSeq, Oct 2010
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Other Versions
SKU Description Size Price
KN407915 GCLC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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