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Human GFI1 activation kit by CRISPRa

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SKU
GA101784
GFI1 CRISPRa kit - CRISPR gene activation of human growth factor independent 1 transcriptional repressor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA805544 GFI1 mouse monoclonal antibody, clone OTI6E8 (formerly 6E8) 100 ul
$447.00
RC207574 GFI1 (Myc-DDK-tagged)-Human growth factor independent 1 transcription repressor (GFI1), transcript variant 1
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Other products for "GFI1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GFI1
Locus ID 2672
Components

GA101784G1, GFI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101784G2, GFI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101784G3, GFI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001127215, NM_001127216, NM_005263
UniProt ID Q99684
Synonyms GFI-1; GFI1A; SCN2; ZNF163
Summary This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN407574 GFI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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