Human GFAP activation kit by CRISPRa

SKU GA101782

GFAP CRISPRa kit - CRISPR gene activation of human glial fibrillary acidic protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GFAP
• Locus ID: 2670
• Components:

  GA101782G1, GFAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101782G2, GFAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101782G3, GFAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001131019, NM_001242376, NM_002055, NM_001363846
• UniProt ID: P14136
• Synonyms: ALXDRD
• Summary: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]