Human FYN activation kit by CRISPRa

SKU GA101683

FYN CRISPRa kit - CRISPR gene activation of human FYN proto-oncogene, Src family tyrosine kinase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FYN
• Locus ID: 2534
• Components:

  GA101683G1, FYN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101683G2, FYN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101683G3, FYN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001242779, NM_002037, NM_153047, NM_153048, NM_001370529
• UniProt ID: P06241
• Synonyms: MGC45350; SLK; SYN
• Summary: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]